![]() ![]() ![]() ![]() OAP% correlated with the transfer lung factor for carbon monoxide (Tlco) (r = 0.64 P = 0.002), the transfer coefficient (Kco) (r = 0.75 P = 0.001), the arterial partial pressure (r = 0.77 P < 0.001), and the saturation (r = 0.70 P < 0.001) of oxygen. The mean OAP% of patients was significantly lower than that of volunteers (36.7 vs. The number of oxygen-activated pixels over the total number of pixels in the ROIs (OAP%) of volunteers and patients was compared. Cross-correlation was performed in regions of interest (ROIs) encompassing both lungs. The paradigm room-air–oxygen–room-air was acquired with a nonselective inversion-recovery half-Fourier single-shot turbo spin-echo sequence (inversion time = 1200 msec acquisition time = 134.5 msec slice thickness = 20 mm matrix size = 128 × 128), using simultaneous double triggering (navigator plus ECG trigger). Materials and MethodsĪ total of 12 healthy volunteers (aged 20–32 years) and 10 patients (aged 37–87 years) with interstitial lung diseases (ILD) underwent oxygen-enhanced MRI and pulmonary functional tests (PFTs) assessing alveolar-capillary gas exchange. ![]() To correlate oxygen-enhanced MRI with lung function tests assessing alveolar-capillary gas exchange. To evaluate an optimized method for oxygen-enhanced MRI of the lung, using simultaneous electrocardiograph (ECG) and navigator triggering. ![]()
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